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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '473e8b10dbd7504146e4ecccaf6de6f6d4d15a31c094be2631cd60ef48d87bfe' 
  AND token = 'DypE0T537UJOnXQ/YcBoTgsAL5t+oO1bkPCnTj3ubdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}