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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed18b8fcada3d8414d83601a29aee619848bd17630100653330f188b6322f01' 
  AND token = 'khM2li45qru1Yi6O6C9cXc0+TMgcVFa7Wlss0lt7D2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}