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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c74fe0adc063bbdb4e522811e683379417dff2957860aa440d26e6eed2bad18' 
  AND token = '9Klz7/P731YOoWuyyhT3dgA4YVfq5hdTuc8vZq4jpWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}