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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd320aff2d0d44d84da88ca3d922d739b2a9b22c321375668dc7fe7a63bd764e5' 
  AND token = 'GTxhumsbAXLmCSmhLq5oT4GurCkRE/8itqGutlBzTZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}