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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '914656078f43991f8c2e92072b0151f10671f1275cde86b3a7a175505c3ed5ac' 
  AND token = 'S4CT3jmUPxZ8tM+JMZPX15olMnaT7sXeq4uhnlVQUzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}