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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ca43583f26157063519c9746e3836c1dc18e4beee6ba6f3341751bb5eaef304' 
  AND token = '/x3EBbOLDIcMb9kdG2dhIV8KPB6aI/8Q1setlxwgBPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}