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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2741d42a9a736b03d8bcc8e363013094753f9e9c8dbdd585875b94373ad25da' 
  AND token = 'a1WgaGFAGuncuAOepsg8kBW6DCY3GUPYzNNzBG8JBfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}