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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9091b125841c2ecca4a3011bf4d00801597656b07cd33a4448047d0bb6daea3' 
  AND token = 'FPi64kD3V3d/C2/L9/wg5+szPe0uhV8NQwhpQKfVDDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}