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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e64aeb6fe4b47428742592fde24cfb8b62bbe419e461e191807d377e77a924a2' 
  AND token = '+SWxmfPL0OhknPFxatPnYrihy95ZCZFuQlp/I8JBzlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}