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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a77137aadebb133a53f78a577570a5b1596c530a558f7477af1b7114127ba0d' 
  AND token = 'sYaZXxt1Xg9SLi3H8dOO+TRabMBnRjd43U0rxGf3nJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}