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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e1a3a6e4ab4fd9170a8493a8ca49593aa6d5c23aaba8ad80656409f326a05e2' 
  AND token = 'Z8S0TvCLLEvBT+mT9BPHfaAStszQdB8Wx8m5wU/6Kgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}