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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e707e80d7a3e18b237cc41e0b22360583551d73f18e06a03f14765bdd4268f5a' 
  AND token = '5Lc1WQ33esSuSgGufrYS0u3DVAqIJ+BM862QsWNJOGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}