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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b197c1d3715eba52aa7fc0136afdefaa5b0787fe8341f459bb6efd443721b69' 
  AND token = 'w1GdulJm004gbmbAXFT3RlvMKAzSJ3zge4Lj6vcUk7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}