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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69f0577575ffff4f4f08af8446cd0e7b0b9e026e247d429d7559540e1b2e9270' 
  AND token = 'RGuM/TsdNTzp85OZ0Mi6/V8xiPJipt/ATUmrHqcaFPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}