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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5501da3d7b665edd4afc1b22c05b32ea16e3c7483fb6d2b4ac6bc99162e9e004' 
  AND token = 'Iu1WlmxFjSs12UHiIIv5658NuqihSL4ywS2fmcxfZE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}