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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de29857a7eeda6b7efe960b54dcdb81f05778238dc71cfa833338045a2f53e23' 
  AND token = '4z6zVEs3oNwpi8pYFfF4RPCrSA6WXGVcQweqhBencLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}