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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c074dddedea00f1e3b57e0e888ab9ec5dbceb4349003d361f07be26b6e5a2779' 
  AND token = 'YCI787IosIkd05/i3KwS7NWdehNPz53cibfSCZNi7rQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}