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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b59d32c3420fd0c0b2d178f0b3c689bf46bf06c4a47991833e350942e32e5e0' 
  AND token = '5kHpOkqriMx/uUELlkGYwAqeqf40KA7tw+RCCv03HuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}