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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5ff6aafea7c13a730b2e812f75137465b68be928a8d58fbd4a3e29851173c8f' 
  AND token = 'V7PY0DY/a3eynVhnhVRJOCzv3gcroqAiFsifeI5C6+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}