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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14828ad683c07bc2fa8711ac482bd979f4db3b06413a0278da5e98f5bb9afccb' 
  AND token = 'mjM3vt213Xi9XDzuuRbToT1Zg0HWA9YjSXOe6PZ9hnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}