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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5be58a4ce409de3733b0fe13aae87be367e94b5cebc4ef37f31e3239cbcb85c' 
  AND token = 'Tou81TH5CnLL9t8j+2tK78LYUibVRkNfEO6qo1Wx2UQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}