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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b027969d8bd5663013fbdb6e915c9153dc655bbaea0619faa57e5d4299cd38f' 
  AND token = 'ND2Q3SAyBRMjL6uNo2Ht/fidFYfrY1UwG4KstBalJvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}