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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '597ebd1861eb6421d726e251ce08b027115878721187d9bacb5683c40b817c8c' 
  AND token = 'sKnNk6PnxrswBKt2h+B+PSSpZapPaF7M+3V7W7xs+i4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}