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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5e5967808f30b7afc703d01814220b796a55b875900cf677f9ef2313a790900' 
  AND token = 'JEwh4G7j6nqfvMPL75hUllSh3Q9iVVWMGpkMr8RgmrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}