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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6408bd1b903e08e3ac1403f1056909c15b6720a59403afac3a8b1fed9fa8f772' 
  AND token = 'phma67tPGowo5BDTJXzn7AfQ5Hk7mMZLv3VrBxeQ5A0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}