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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5482559cf8d3c738e0737b2cb72013c9394661ea6e36c9d8790798bb83d92c6' 
  AND token = 't/Ec8NRYcLz5yCZwG81lpjK+6rrdrsEwwKyUkX6CQUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}