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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a743577d6e8957733c12b4efdc893407a1a5c5571ccab04714f29b25dbc45998' 
  AND token = 'I+YiotUuxYDLcg5bfHN4l9QAV3CQsNqhZru+fDNVLJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}