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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99e3dab72b3ab1632f406a7a7635d20ae451038d79b4b2e15abedd6bcbfb278a' 
  AND token = 'OI/3FT72bpAxXTo4L7JWkXy/D0bEcBYQpFVV8dA4yPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}