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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17bce11e0f4d00cae0e1e54c610a906ff20d7e456b11031ee4f0a6188a2e3ce3' 
  AND token = 'hRLPgNUIOqXB2F9yWhC6RT5Gq8psq9i3BGwOl3MwO9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}