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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eb3155329de48403b4411bcd82d63bb9149a41d93e5120a5c5f6a27470dadfe' 
  AND token = '+kLXVVIQ/OJLaM4IZSroufG4DHxPvmw73p0uvk7Mj+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}