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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03f125d54ecdda869b7bc45c8ccbe8014f5e5cd8e96498d4dce788fea925dae4' 
  AND token = 'iT3w/EjbbdZ6hc0l1RLoWs0yBz5Vtg/3JM7VPNndtrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}