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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f1b19878595a166a0fa9cb09a0e360e51b98cd020c1948e27dff3c7b3a674f6' 
  AND token = 'HdWBubZFLepqKVoSWm8gcsH0MgA+EqqwpcRzOpdXTAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}