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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd5c25a2cbcce4bab057baf3f78e9c02161dc9bd043cf16d1edeaf21f55e165c' 
  AND token = '8TUefzkXwI2U9ch8IJ8e/+PHgNDXnpOYwU8TO2B7D0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}