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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18187b975c055c2526f06ab0f0b8c9d81c7c19bb33ff959ee75c1cb8e4a204b3' 
  AND token = 'DuAi3dhUIRDshaXwZDipkmV2dd7FcdDEbP+TSIbuI80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}