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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '114f168ed7e85f62fa15d9df8fba35b04e78e6612a8731b72d27de6d477dde68' 
  AND token = 'Yv3e9y1GNO7pW6tjE3xmW8j5nEYW8k5VC9D+NLeGv9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}