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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b0536540e06d30eb6f27fa5677b722c285d343e4065268c4e5348247ee4edad' 
  AND token = '+F10qj5KIkdDF1rcXtrWsguOBKo6dwe2EL1ksxrWYwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}