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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '201a91fe777708e8d66dff31ca83aa2ae1efbbb958a2daa06d59f73b55606e70' 
  AND token = 'fr1KEHNdkcMx+XbD7hiwbfzttTE8ataFoKWzAkHvfwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}