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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44cc08af99362325d49229d70002cc78a7fc1203cbad6536db79ddab678ec404' 
  AND token = '/TWVlgs5PAeelzMt2X91qjJpllVlxh/xhliQiCztceQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}