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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eee14b055aa7bbb5fc46b4a2f1d90bb821416fb95c24a7fed8226ed9e5691291' 
  AND token = 'lOV3bZOu8HoNodD0Se4urKArAk+GueWtmWjwUDI2gyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}