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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acd4f9c5a827e65d34690aa804e25bbc2aabe9ee39328c4190d36a154c8bb338' 
  AND token = 'Xn/tXYIVkk5KVa1Y4m9rUhC1Ph1ckQD7E0hFDpTe2us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}