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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6d54530755615d1deace7576c2d555ce984de150674b47f44b54e46a1be21b5' 
  AND token = 'NNjtu9KKDKugW0Al4+00NjTjdAoRuRu8SVpvLV1Ebx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}