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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fcd7052bee9195010146a05a627dacea1296f66fa9971c469e27b22aa9ae63f' 
  AND token = 'MTTb/Yx43Qi/hjogsxlLO4Mo+OyFWDJfJ9u6hWnX/6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}