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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0684f3bb5bae585792b669c47e58d4cb38fccef9e4bf6b3e9b6b15940d5b543' 
  AND token = '6IqUl35jA8UJ/WImoT0NpOiqWlu2wMX0ofDidNZrEGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}