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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b563b4323202f2323f37ce0b97b95664429356ebbdf6ae78a49d7c7bdd72e9' 
  AND token = 'qNrk4ibRLZaMe6BuSsXU0A5jTBkeywUlKOcHZuPiLFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}