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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eb1293c4b6dc398cb975397e93191bcd5f1e2caa1965d497e7a2e4c4aeceb20' 
  AND token = '1OCxevKne0nKpl2O0E2IlxGpqZd0UmMQCIAysJU/+1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}