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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2adc44c4e86f5444bd3c846ed263ee8568581f1e121b1a1f8f33b716bedc0b1' 
  AND token = 'o5sO8HkyuDZpKR/+wOv+ps9aayxeDq3XwVL7oxBfwbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}