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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff6ef064ff27db90936ddd1f209e988b25a1a246d700fc5d5b7f151250223ee2' 
  AND token = '7vId6T82jtDdc62btplKPY72G9KAeHdyRTokkzfFLI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}