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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b00e11c06cb0fd635ba1fd3752dbad8ceb67ce624f251fa4920eb4bc31a6add' 
  AND token = '5knX83ie9t8YO/j2doRjLaqzyONthb+sJy3K9lP/MpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}