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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dfb97e40686ff2450ef85d4c2a77085a43e652b59220baf60f56244465a8fc0' 
  AND token = 'tN27/mrj55CPxdM+rPJoDEsn7G9ejqoK4ZF9ZWciQcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}