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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e51a7002c4ebfc8bb26e7526587e06f58effa6103eb8f1d7b0e586aa2676e2d6' 
  AND token = 'vDYFJUN3RsOEgFpot7eziYm/s74FYF7lzK0RNJnwEr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}